Cell Sense & Cell Tracking - Papers

Studies involving Celsense products:

Non-invasive imaging of transplanted human neural stem cells and ECM scaffold remodeling in the stroke-damaged rat brain by (19)F- and diffusion-MRI.
Bible E, Dell’acqua F, Solanky B, Balducci A, Crapo PM, Badylak SF, Ahrens ET, Modo M. Biomaterials. 2012 Jan 12. [Epub ahead of print]

In vivo tracking of human neural stem cells with (19)F magnetic resonance imaging.
Boehm-Sturm P, Mengler L , Wecker S, Hoehn M, Kallur T, 2011. PLoS ONE 6(12): e29040.

A novel (19)F agent for detection and quantification of human dendritic cells using magnetic resonance imaging.
Bonetto F, Srinivas M, Heerschap A, Mailliard R, Ahrens ET, Figdor CG, de Vries IJ. Int J Cancer. 2011 Jul 15;129(2):365-73.

Functional assessment of human dendritic cells labeled for in vivo (19)F magnetic resonance imaging cell tracking.
Helfer BM, Balducci A, Nelson AD, Janjic JM, Gil RR, Kalinski P, de Vries IJ, Ahrens ET, Mailliard RB. Cytotherapy. 2010 Apr;12(2):238-50.

Studies involving other perfluorocarbon emulsions:

Inflammation driven by overexpression of the hypoglycosylated abnormal mucin 1 (MUC1) links inflammatory bowel disease and pancreatitis.
Kadayakkara DK, Beatty PL, Turner MS, Janjic JM, Ahrens ET, Finn OJ. Pancreas. 2010 May;39(4):510-5.

In vivo observation of intracellular oximetry in perfluorocarbon-labeled glioma cells and chemotherapeutic response in the CNS using fluorine-19 MRI.
Kadayakkara DK, Janjic JM, Pusateri LK, Young WB, Ahrens ET. Magn Reson Med. 2010 Nov;64(5):1252-9.

In vivo cytometry of antigen-specific t cells using (19)F MRI.
Srinivas M, Turner MS, Janjic JM, Morel PA, Laidlaw DH, Ahrens ET. Magn Reson Med. 2009 Sep;62(3):747-53.

Fluorine-19 MRI for visualization and quantification of cell migration in a diabetes model.
Srinivas M, Morel PA, Ernst LA, Laidlaw DH, Ahrens ET. Magn Reson Med. 2007 Oct;58(4):725-34.

In vivo imaging platform for tracking immunotherapeutic cells.
Ahrens ET, Flores R, Xu H, Morel PA. Nat Biotechnol. 2005 Aug;23(8):983-7.

Abstracts

(19)F MRI cellular tracer preserves the differentiation potential of hematopoietic stem cells. Helfer B, Balducci A, Wesa A. 9th Annual Meeting of the International Society for Stem Cell Research, Toronto, Canada, June 15-18, 2011.

Labeling of T cells and NK cells with a clinically-applicable perfluorocarbon for quantitative (19)F MRI tracking in cancer patients. Helfer B, Balducci A, Mailliard R, and Wesa A. 25th Annual Meeting of International Society for Biological Therapy of Cancer, Washington, DC; Oct 2-4, 2010.

Characterization of an F-19 MRI contrast agent in human NSCs for transplantation into stroked-lesioned brain. Bible E, Solanky B, Ahrens ET, Modo M. Cell Transplant 2010;19(3):331-331.

Clinically-compatible (19)F NMR tracking of DC vaccines in vivo. Urban J, Helfer B, Thorne S, Ahrens E, Wesa A, Kalinski P. J Immunother 2010;33(8):880-880.

F19 Labeling of human alpha-type-1-polarized dendritic cells and standard dendritic cells for in vivo trafficking by fluorine MRI. Helfer BM, Balducci A, Mailliard R, Ahrens E, Kalinski P, Wesa A. J Immunother 2010;33(8):878-878.

In vitro/in vivo MRI visualization of PFC/VSOP double-labeled mesenchymal stem cells. Kampf T, Basse-Lüsebrink TC, Weber M, Heymer A, Ebert R, Stoetzel C, Gbureck U, Noeth U, Jakob PM, Bauer WR, Haddad D. In: Proceedings of the 16th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Toronto, Ontario, Canada. Abstract #1692.